Clinical
Empagliflozin Started Within 72 Hours of a Heart Attack Improved Cardiac Biomarkers and Echocardiographic Parameters at 26 Weeks
European Heart Journal · 8 min
This week's review
Clinical
Empagliflozin Started Within 72 Hours of a Heart Attack Improved Cardiac Biomarkers and Echocardiographic Parameters at 26 Weeks
von Lewinski D, Kolesnik E, Tripolt NJ, et al.
European Heart Journal · April 19, 2026 · 8 min read
The EMMY trial found that empagliflozin started within 72 hours of large acute MI improved NT-proBNP and echocardiographic parameters at 26 weeks — but the subsequent EMPACT-MI trial did not show a reduction in hard clinical outcomes.
Read this week's review → Key numbers
476
Patients enrolled
15%
NT-proBNP reduction
1.5%
LVEF improvement
26 weeks
Follow-up
"Empagliflozin started within 72 hours of a heart attack improved cardiac biomarkers and echocardiographic parameters at 26 weeks. Whether that improvement translates to fewer hospitalizations and deaths is a different question, and a harder one."
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Empagliflozin Started Within 72 Hours of a Heart Attack Improved Cardiac Biomarkers and Echocardiographic Parameters at 26 Weeks
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8
Publications
3
Research domains
1
Book chapter
9
Presentations
About the editor
Editor & founder
Kameron Farhadi
Former Dental Student · Pre-Medical Student · Researcher
CliniScope Weekly exists because the gap between medical research and clinical understanding is too wide. Each review translates one peer-reviewed study into something a pre-medical student and a seasoned attending can both learn from. Kameron's work spans 8 publications across clinical epidemiology, public health, and health policy — including one peer-reviewed textbook chapter.
8
Publications
3
Domains
1
Book chapter
9
Presentations
EpidemiologyImplantologyPreventive MedicineHealth EquityPopulation Health
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