One peer-reviewed article. One honest take. Every week.
Issue 23 · Scientific Reports · September 6, 2026 · 9 min read
73 astronauts. 34 deaths. A standardized mortality ratio for cancer of 43, meaning astronauts died of cancer at less than half the rate of the general population. This is not evidence that spaceflight prevents cancer. It is a textbook illustration of one of epidemiology's oldest and most important traps.
Read this week's review →"This cohort will never be large enough to detect the radiation risks predicted by decades of terrestrial radiation research, no matter how long follow-up continues."
73 Astronauts. 34 Deaths. A Standardized Mortality Ratio for Cancer of 43, Meaning Astronauts Died of Cancer at Less Than Half the Rate of the General Population. This Is Not Evidence That Spaceflight Prevents Cancer.
Scientific Reports
442,027 People. A Ten-Year Follow-Up. One Question Asked at Enrollment: How Many Times a Day Do You Climb a Flight of Stairs at Home? People Who Answered 'More Than 15' Had a Lower Risk of 8 Out of 9 Major Chronic Diseases Studied.
American Journal of Preventive Medicine
Over 14 Years at One Major Cardiac Center, the Average Patient Undergoing Open Aortic Valve Replacement Got Six Years Younger. The Average Patient Undergoing Coronary Bypass Got Healthier, Not Sicker.
Journal of Clinical Medicine
Six Months Aboard the International Space Station Induces Cardiovascular Changes Comparable to More Than a Decade of Healthy Aging on Earth. NASA Has Spent 50 Years Learning to Reverse It. That Knowledge May Now Be Worth More to Cardiologists on Earth Than to Astronauts in Orbit.
Circulation Research
"When Does Trauma Ever Become Post?" A Paramedic Asked That Question During a Research Interview, and It Captures Something the Standard PTSD Diagnosis Was Never Built to Hold.
Healthcare
Statin-Associated Muscle Symptoms Affect Between 7 and 29 Percent of People Who Take These Medications and Are the Most Common Reason Patients Stop a Drug That Could Save Their Life. Researchers Have Now Identified the Specific Biological Pathway Responsible.
Science Advances
Since May 1, 2026, More Than 1,645 Confirmed Cases of Cyclosporiasis Have Been Reported Across 34 States. More Than 5,100 Additional Cases Are Under Investigation. The Source Is Shredded Iceberg Lettuce Served at Taco Bell.
CDC
AI Research in Anesthesiology Grew From a Niche Interest to a Substantial Field Over Twenty Years, With a Sharp Surge After 2019. The Three Areas Driving That Growth Are Perioperative Risk Prediction, AI-Assisted Ultrasound Guidance, and Intelligent Monitoring.
Frontiers in Medicine
In 2023, Tuberculosis Reclaimed Its Position as the World's Leading Cause of Death From a Single Infectious Agent, Surpassing COVID-19. With 10.8 Million New Cases and 1.25 Million Deaths in One Year Alone, TB Is Not a Disease of the Past.
International Journal of Infectious Diseases
From 1999 to 2023, Heat-Related Deaths in the United States More Than Doubled. Between 2016 and 2023, the Age-Adjusted Mortality Rate Increased by 16.8% Per Year. This Is Not a Slow Trend. It Is an Acceleration.
JAMA
Across 22 Randomized Trials and Over 32,000 Patients, Semaglutide Nearly Doubled the Rate of Liver Disease Resolution. It Did Not Significantly Reverse the Scarring That Actually Determines Long-Term Outcomes.
Diabetology & Metabolic Syndrome
A Father's Health Before Conception Can Alter the Development of the Placenta in His Future Child, According to a Growing Body of Animal Research.
Frontiers in Genetics
In 2021, 4.71 Million Deaths Were Associated With Bacterial Antimicrobial Resistance Worldwide. By 2050, That Number Is Projected to Reach 8.22 Million Per Year.
The Lancet
In 2017, Firearms Surpassed Motor Vehicle Collisions as the Leading Cause of Death Among American Adolescents Aged 11 to 18. June is National Gun Violence Awareness Month.
Injury Epidemiology
In December 2023 the FDA Approved the First Therapy to Use CRISPR/Cas9 Gene Editing Technology in Humans. The Disease it Targets, Sickle Cell Disease, Has Been Treatable but Never Curable for the 100,000 Americans Living With It.
Annals of Medicine and Surgery
Two Outbreaks Are Active Simultaneously. One Began on a Cruise Ship Crossing the South Atlantic. The Other Is Spreading Across Eastern Democratic Republic of the Congo and Has Now Reached Uganda.
WHO · CDC · ECDC
Between 2010 and 2019, Cancer Incidence Among Americans Under 50 Increased Overall, With the Steepest Rises in the 30 to 39 Age Group. Gastrointestinal Cancers Drove the Fastest Growth.
JAMA Network Open
Depression and Anxiety Affect Up to One in Four Pregnancies in the United States. Pregnant People Are Less Likely to Be Screened for These Conditions Than at Any Other Point in Their Lives.
Journal of Midwifery and Women's Health
Lecanemab Slowed Alzheimer's Disease Progression by 27% at 18 Months. That Number is Real. Understanding What it Means for an Individual Patient and Family is a Different and Harder Conversation.
Alzheimer's Research and Therapy
Fifteen Conditions Account for More Than 80% of the Global Life Expectancy Gap Between the World's Healthiest and Least Healthy Populations
JAMA Network Open
Empagliflozin Started Within 72 Hours of a Heart Attack Improved Cardiac Biomarkers and Echocardiographic Parameters at 26 Weeks
European Heart Journal
A Systematic Review of 30 Studies Found That Large Language Models Can Match or Outperform Clinicians on Structured Diagnostic Tasks
JMIR Medical Informatics
Nine Years of Progress in Cardiovascular Mortality Were Reversed Between 2019 and 2022
American Journal of Preventive Medicine
73 Astronauts. 34 Deaths. A Standardized Mortality Ratio for Cancer of 43, Meaning Astronauts Died of Cancer at Less Than Half the Rate of the General Population. This Is Not Evidence That Spaceflight Prevents Cancer.
Scientific Reports
442,027 People. A Ten-Year Follow-Up. One Question Asked at Enrollment: How Many Times a Day Do You Climb a Flight of Stairs at Home? People Who Answered 'More Than 15' Had a Lower Risk of 8 Out of 9 Major Chronic Diseases Studied.
American Journal of Preventive Medicine
Over 14 Years at One Major Cardiac Center, the Average Patient Undergoing Open Aortic Valve Replacement Got Six Years Younger. The Average Patient Undergoing Coronary Bypass Got Healthier, Not Sicker.
Journal of Clinical Medicine
Six Months Aboard the International Space Station Induces Cardiovascular Changes Comparable to More Than a Decade of Healthy Aging on Earth. NASA Has Spent 50 Years Learning to Reverse It. That Knowledge May Now Be Worth More to Cardiologists on Earth Than to Astronauts in Orbit.
Circulation Research
"When Does Trauma Ever Become Post?" A Paramedic Asked That Question During a Research Interview, and It Captures Something the Standard PTSD Diagnosis Was Never Built to Hold.
Healthcare
Statin-Associated Muscle Symptoms Affect Between 7 and 29 Percent of People Who Take These Medications and Are the Most Common Reason Patients Stop a Drug That Could Save Their Life. Researchers Have Now Identified the Specific Biological Pathway Responsible.
Science Advances
Since May 1, 2026, More Than 1,645 Confirmed Cases of Cyclosporiasis Have Been Reported Across 34 States. More Than 5,100 Additional Cases Are Under Investigation. The Source Is Shredded Iceberg Lettuce Served at Taco Bell.
CDC
AI Research in Anesthesiology Grew From a Niche Interest to a Substantial Field Over Twenty Years, With a Sharp Surge After 2019. The Three Areas Driving That Growth Are Perioperative Risk Prediction, AI-Assisted Ultrasound Guidance, and Intelligent Monitoring.
Frontiers in Medicine
In 2023, Tuberculosis Reclaimed Its Position as the World's Leading Cause of Death From a Single Infectious Agent, Surpassing COVID-19. With 10.8 Million New Cases and 1.25 Million Deaths in One Year Alone, TB Is Not a Disease of the Past.
International Journal of Infectious Diseases
From 1999 to 2023, Heat-Related Deaths in the United States More Than Doubled. Between 2016 and 2023, the Age-Adjusted Mortality Rate Increased by 16.8% Per Year. This Is Not a Slow Trend. It Is an Acceleration.
JAMA
Across 22 Randomized Trials and Over 32,000 Patients, Semaglutide Nearly Doubled the Rate of Liver Disease Resolution. It Did Not Significantly Reverse the Scarring That Actually Determines Long-Term Outcomes.
Diabetology & Metabolic Syndrome
A Father's Health Before Conception Can Alter the Development of the Placenta in His Future Child, According to a Growing Body of Animal Research.
Frontiers in Genetics
In 2021, 4.71 Million Deaths Were Associated With Bacterial Antimicrobial Resistance Worldwide. By 2050, That Number Is Projected to Reach 8.22 Million Per Year.
The Lancet
In 2017, Firearms Surpassed Motor Vehicle Collisions as the Leading Cause of Death Among American Adolescents Aged 11 to 18. June is National Gun Violence Awareness Month.
Injury Epidemiology
In December 2023 the FDA Approved the First Therapy to Use CRISPR/Cas9 Gene Editing Technology in Humans. The Disease it Targets, Sickle Cell Disease, Has Been Treatable but Never Curable for the 100,000 Americans Living With It.
Annals of Medicine and Surgery
Two Outbreaks Are Active Simultaneously. One Began on a Cruise Ship Crossing the South Atlantic. The Other Is Spreading Across Eastern Democratic Republic of the Congo and Has Now Reached Uganda.
WHO · CDC · ECDC
Between 2010 and 2019, Cancer Incidence Among Americans Under 50 Increased Overall, With the Steepest Rises in the 30 to 39 Age Group. Gastrointestinal Cancers Drove the Fastest Growth.
JAMA Network Open
Depression and Anxiety Affect Up to One in Four Pregnancies in the United States. Pregnant People Are Less Likely to Be Screened for These Conditions Than at Any Other Point in Their Lives.
Journal of Midwifery and Women's Health
Lecanemab Slowed Alzheimer's Disease Progression by 27% at 18 Months. That Number is Real. Understanding What it Means for an Individual Patient and Family is a Different and Harder Conversation.
Alzheimer's Research and Therapy
Fifteen Conditions Account for More Than 80% of the Global Life Expectancy Gap Between the World's Healthiest and Least Healthy Populations
JAMA Network Open
Empagliflozin Started Within 72 Hours of a Heart Attack Improved Cardiac Biomarkers and Echocardiographic Parameters at 26 Weeks
European Heart Journal
A Systematic Review of 30 Studies Found That Large Language Models Can Match or Outperform Clinicians on Structured Diagnostic Tasks
JMIR Medical Informatics
Nine Years of Progress in Cardiovascular Mortality Were Reversed Between 2019 and 2022
American Journal of Preventive Medicine
73 Astronauts. 34 Deaths. A Standardized Mortality Ratio for Cancer of 43, Meaning Astronauts Died of Cancer at Less Than Half the Rate of the General Population. This Is Not Evidence That Spaceflight Prevents Cancer.
Scientific Reports
442,027 People. A Ten-Year Follow-Up. One Question Asked at Enrollment: How Many Times a Day Do You Climb a Flight of Stairs at Home? People Who Answered 'More Than 15' Had a Lower Risk of 8 Out of 9 Major Chronic Diseases Studied.
American Journal of Preventive Medicine
Over 14 Years at One Major Cardiac Center, the Average Patient Undergoing Open Aortic Valve Replacement Got Six Years Younger. The Average Patient Undergoing Coronary Bypass Got Healthier, Not Sicker.
Journal of Clinical Medicine
Six Months Aboard the International Space Station Induces Cardiovascular Changes Comparable to More Than a Decade of Healthy Aging on Earth. NASA Has Spent 50 Years Learning to Reverse It. That Knowledge May Now Be Worth More to Cardiologists on Earth Than to Astronauts in Orbit.
Circulation Research
"When Does Trauma Ever Become Post?" A Paramedic Asked That Question During a Research Interview, and It Captures Something the Standard PTSD Diagnosis Was Never Built to Hold.
Healthcare
Statin-Associated Muscle Symptoms Affect Between 7 and 29 Percent of People Who Take These Medications and Are the Most Common Reason Patients Stop a Drug That Could Save Their Life. Researchers Have Now Identified the Specific Biological Pathway Responsible.
Science Advances
Since May 1, 2026, More Than 1,645 Confirmed Cases of Cyclosporiasis Have Been Reported Across 34 States. More Than 5,100 Additional Cases Are Under Investigation. The Source Is Shredded Iceberg Lettuce Served at Taco Bell.
CDC
AI Research in Anesthesiology Grew From a Niche Interest to a Substantial Field Over Twenty Years, With a Sharp Surge After 2019. The Three Areas Driving That Growth Are Perioperative Risk Prediction, AI-Assisted Ultrasound Guidance, and Intelligent Monitoring.
Frontiers in Medicine
In 2023, Tuberculosis Reclaimed Its Position as the World's Leading Cause of Death From a Single Infectious Agent, Surpassing COVID-19. With 10.8 Million New Cases and 1.25 Million Deaths in One Year Alone, TB Is Not a Disease of the Past.
International Journal of Infectious Diseases
From 1999 to 2023, Heat-Related Deaths in the United States More Than Doubled. Between 2016 and 2023, the Age-Adjusted Mortality Rate Increased by 16.8% Per Year. This Is Not a Slow Trend. It Is an Acceleration.
JAMA
Across 22 Randomized Trials and Over 32,000 Patients, Semaglutide Nearly Doubled the Rate of Liver Disease Resolution. It Did Not Significantly Reverse the Scarring That Actually Determines Long-Term Outcomes.
Diabetology & Metabolic Syndrome
A Father's Health Before Conception Can Alter the Development of the Placenta in His Future Child, According to a Growing Body of Animal Research.
Frontiers in Genetics
In 2021, 4.71 Million Deaths Were Associated With Bacterial Antimicrobial Resistance Worldwide. By 2050, That Number Is Projected to Reach 8.22 Million Per Year.
The Lancet
In 2017, Firearms Surpassed Motor Vehicle Collisions as the Leading Cause of Death Among American Adolescents Aged 11 to 18. June is National Gun Violence Awareness Month.
Injury Epidemiology
In December 2023 the FDA Approved the First Therapy to Use CRISPR/Cas9 Gene Editing Technology in Humans. The Disease it Targets, Sickle Cell Disease, Has Been Treatable but Never Curable for the 100,000 Americans Living With It.
Annals of Medicine and Surgery
Two Outbreaks Are Active Simultaneously. One Began on a Cruise Ship Crossing the South Atlantic. The Other Is Spreading Across Eastern Democratic Republic of the Congo and Has Now Reached Uganda.
WHO · CDC · ECDC
Between 2010 and 2019, Cancer Incidence Among Americans Under 50 Increased Overall, With the Steepest Rises in the 30 to 39 Age Group. Gastrointestinal Cancers Drove the Fastest Growth.
JAMA Network Open
Depression and Anxiety Affect Up to One in Four Pregnancies in the United States. Pregnant People Are Less Likely to Be Screened for These Conditions Than at Any Other Point in Their Lives.
Journal of Midwifery and Women's Health
Lecanemab Slowed Alzheimer's Disease Progression by 27% at 18 Months. That Number is Real. Understanding What it Means for an Individual Patient and Family is a Different and Harder Conversation.
Alzheimer's Research and Therapy
Fifteen Conditions Account for More Than 80% of the Global Life Expectancy Gap Between the World's Healthiest and Least Healthy Populations
JAMA Network Open
Empagliflozin Started Within 72 Hours of a Heart Attack Improved Cardiac Biomarkers and Echocardiographic Parameters at 26 Weeks
European Heart Journal
A Systematic Review of 30 Studies Found That Large Language Models Can Match or Outperform Clinicians on Structured Diagnostic Tasks
JMIR Medical Informatics
Nine Years of Progress in Cardiovascular Mortality Were Reversed Between 2019 and 2022
American Journal of Preventive Medicine
73 Astronauts. 34 Deaths. A Standardized Mortality Ratio for Cancer of 43, Meaning Astronauts Died of Cancer at Less Than Half the Rate of the General Population. This Is Not Evidence That Spaceflight Prevents Cancer.
Scientific Reports
442,027 People. A Ten-Year Follow-Up. One Question Asked at Enrollment: How Many Times a Day Do You Climb a Flight of Stairs at Home? People Who Answered 'More Than 15' Had a Lower Risk of 8 Out of 9 Major Chronic Diseases Studied.
American Journal of Preventive Medicine
Over 14 Years at One Major Cardiac Center, the Average Patient Undergoing Open Aortic Valve Replacement Got Six Years Younger. The Average Patient Undergoing Coronary Bypass Got Healthier, Not Sicker.
Journal of Clinical Medicine
Six Months Aboard the International Space Station Induces Cardiovascular Changes Comparable to More Than a Decade of Healthy Aging on Earth. NASA Has Spent 50 Years Learning to Reverse It. That Knowledge May Now Be Worth More to Cardiologists on Earth Than to Astronauts in Orbit.
Circulation Research
"When Does Trauma Ever Become Post?" A Paramedic Asked That Question During a Research Interview, and It Captures Something the Standard PTSD Diagnosis Was Never Built to Hold.
Healthcare
Statin-Associated Muscle Symptoms Affect Between 7 and 29 Percent of People Who Take These Medications and Are the Most Common Reason Patients Stop a Drug That Could Save Their Life. Researchers Have Now Identified the Specific Biological Pathway Responsible.
Science Advances
Since May 1, 2026, More Than 1,645 Confirmed Cases of Cyclosporiasis Have Been Reported Across 34 States. More Than 5,100 Additional Cases Are Under Investigation. The Source Is Shredded Iceberg Lettuce Served at Taco Bell.
CDC
AI Research in Anesthesiology Grew From a Niche Interest to a Substantial Field Over Twenty Years, With a Sharp Surge After 2019. The Three Areas Driving That Growth Are Perioperative Risk Prediction, AI-Assisted Ultrasound Guidance, and Intelligent Monitoring.
Frontiers in Medicine
In 2023, Tuberculosis Reclaimed Its Position as the World's Leading Cause of Death From a Single Infectious Agent, Surpassing COVID-19. With 10.8 Million New Cases and 1.25 Million Deaths in One Year Alone, TB Is Not a Disease of the Past.
International Journal of Infectious Diseases
From 1999 to 2023, Heat-Related Deaths in the United States More Than Doubled. Between 2016 and 2023, the Age-Adjusted Mortality Rate Increased by 16.8% Per Year. This Is Not a Slow Trend. It Is an Acceleration.
JAMA
Across 22 Randomized Trials and Over 32,000 Patients, Semaglutide Nearly Doubled the Rate of Liver Disease Resolution. It Did Not Significantly Reverse the Scarring That Actually Determines Long-Term Outcomes.
Diabetology & Metabolic Syndrome
A Father's Health Before Conception Can Alter the Development of the Placenta in His Future Child, According to a Growing Body of Animal Research.
Frontiers in Genetics
In 2021, 4.71 Million Deaths Were Associated With Bacterial Antimicrobial Resistance Worldwide. By 2050, That Number Is Projected to Reach 8.22 Million Per Year.
The Lancet
In 2017, Firearms Surpassed Motor Vehicle Collisions as the Leading Cause of Death Among American Adolescents Aged 11 to 18. June is National Gun Violence Awareness Month.
Injury Epidemiology
In December 2023 the FDA Approved the First Therapy to Use CRISPR/Cas9 Gene Editing Technology in Humans. The Disease it Targets, Sickle Cell Disease, Has Been Treatable but Never Curable for the 100,000 Americans Living With It.
Annals of Medicine and Surgery
Two Outbreaks Are Active Simultaneously. One Began on a Cruise Ship Crossing the South Atlantic. The Other Is Spreading Across Eastern Democratic Republic of the Congo and Has Now Reached Uganda.
WHO · CDC · ECDC
Between 2010 and 2019, Cancer Incidence Among Americans Under 50 Increased Overall, With the Steepest Rises in the 30 to 39 Age Group. Gastrointestinal Cancers Drove the Fastest Growth.
JAMA Network Open
Depression and Anxiety Affect Up to One in Four Pregnancies in the United States. Pregnant People Are Less Likely to Be Screened for These Conditions Than at Any Other Point in Their Lives.
Journal of Midwifery and Women's Health
Lecanemab Slowed Alzheimer's Disease Progression by 27% at 18 Months. That Number is Real. Understanding What it Means for an Individual Patient and Family is a Different and Harder Conversation.
Alzheimer's Research and Therapy
Fifteen Conditions Account for More Than 80% of the Global Life Expectancy Gap Between the World's Healthiest and Least Healthy Populations
JAMA Network Open
Empagliflozin Started Within 72 Hours of a Heart Attack Improved Cardiac Biomarkers and Echocardiographic Parameters at 26 Weeks
European Heart Journal
A Systematic Review of 30 Studies Found That Large Language Models Can Match or Outperform Clinicians on Structured Diagnostic Tasks
JMIR Medical Informatics
Nine Years of Progress in Cardiovascular Mortality Were Reversed Between 2019 and 2022
American Journal of Preventive Medicine
Selected peer-reviewed publications and book contributions authored by Kameron Farhadi across clinical epidemiology, public health, and dentistry.
Farhadi, K. & Romanos, G.E.
Saving Dental Implants — Wiley-Blackwell (Book Chapter)
Peer-reviewed textbook chapter examining plasma cleaning as a surface decontamination strategy for failed or failing dental implants, with a focus on clinical outcomes and implant salvage protocols.
Mercy, U., Farhadi, K., Ogunsola, A., Karaye, R.M., Baguda, U., Olatunji, E., Yunusa, I., & Karaye, I.M.
Journal of the Neurological Sciences
Analysis of 21-year national mortality data characterizing shifting trends in stroke death rates across demographic groups in the United States, with implications for prevention and health policy.
Karaye, I.M., Olokunlade, T., Cevetello, A., Farhadi, K., & Kyriacou, C.M.
Journal of Community Health
Longitudinal trend analysis of motor vehicle traffic fatalities in New York City over a 21-year period, identifying demographic and temporal patterns with implications for urban traffic safety policy.
Yunusa, I., Farhadi, K., & Karaye, I.M.
Journal of Racial and Ethnic Health Disparities
Examination of cocaine-involved overdose mortality trends stratified by race, ethnicity, and US region over two decades, revealing persistent and widening disparities with implications for targeted harm reduction.
Ogunsola, A.S., Farhadi, K., Mercy, U.C., Elenwa, F., Karaye, R.M., Baba, M.J., Eniola, O.A., Yunusa, I., & Karaye, I.M.
Thrombosis Research
National mortality trend analysis for pulmonary embolism spanning 21 years, characterizing age, sex, and race-stratified patterns in PE-related deaths and identifying at-risk subpopulations.
Karaye, I.M., Farhadi, K., Sengstock, G., Shahidullah, S., Taravella, R., & Nasir, R.
Journal of Safety Research
Epidemiological analysis of unintentional drowning fatalities across 21 years of US mortality data, identifying demographic trends and seasonal patterns to inform public safety interventions.
Farhadi, K., Santella, A.J., & Karaye, I.M.
Community Dentistry and Oral Epidemiology
Trend analysis of nasopharyngeal cancer mortality across 21 years of national data, examining race, sex, and age disparities in disease burden with relevance to oral and head-and-neck oncology.
Farhadi, K., Rojanaworarit, C., Bhurosy, T., Olokunlade, T., & Karaye, I.M.
Journal of Oral Pathology & Medicine
Comprehensive mortality trend analysis for lip, oral cavity, and pharyngeal cancers over a 20-year period, stratified by demographic subgroup, highlighting the growing burden of oropharyngeal malignancies.
Editor & founder
Former Dental Student · Pre-Medical Student · Researcher
CliniScope Weekly exists because the gap between medical research and clinical understanding is too wide. Each review translates one peer-reviewed study into something a pre-medical student and a seasoned attending can both learn from. Kameron's work spans 8 publications across clinical epidemiology, public health, and health policy — including one peer-reviewed textbook chapter.
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